Article
[Regenerative potential of the sensory epithelium of the mammalian organ of Corti after poisoning with ototoxic antibiotics].
Morphologie : bulletin de l'Association des anatomistes - 1 Sept 1999
Vago P, Parietti C, Daudet N, Humbert G, Gallégo M, Pujol R, Lenoir M
Abstract excerpt
Cochlear sensory hair cells are very sensitive to noxious influences such as ageing, noise and ototoxic drugs. Whereas lost auditory hair cells are replaced by new hair cells in the avian and lower vertebrates, cochlear sensory hair cells do not regenerate in mammals. Recently, we have observed transient atypical cells in the cochlea of amikacin intoxicated rats. We have related their presence to an attempt at...
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