Apoptosis in acquired and genetic hearing impairment: the programmed death of the hair cell.

Abstract excerpt

Apoptosis is an important physiological process. Normally, a healthy cell maintains a delicate balance between pro- and anti-apoptotic factors, allowing it to live and proliferate. It is thus not surprising that disturbance of this delicate balance may result in disease. It is a well known fact that apoptosis also contributes to several acquired forms of hearing impairment. Noise-induced hearing loss is the...

Topics

• Animals
• Apoptosis
• Genetic Predisposition to Disease
• Hair Cells, Auditory
• Hearing Loss
• Hearing Loss, Noise-Induced
• Humans
• Membrane Proteins
• Methionine Sulfoxide Reductases
• Mutation
• Phenotype