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Article

Macrophage contribution to the response of the rat organ of Corti to amikacin.

Journal of neuroscience research - 1 Jul 2007

Ladrech Sabine, Wang Jing, Simonneau Lionel, Puel Jean-Luc, Lenoir Marc

Abstract excerpt

Transdifferentiation of nonsensory supporting cells into sensory hair cells occurs naturally in the damaged avian inner ear. Such transdifferentiation was achieved experimentally in the cochlea of deaf guinea pigs through Atoh 1 gene transfection. Supporting cells may therefore serve as targets for transdifferentiation therapy. Supporting cells rapidly degenerate after hair cell disappearance, however, limiting...

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Identifiers

PMID: 17497672
DOI: 10.1002/jnr.21335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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