Effect of selection against deleterious mutations on the decline in heterozygosity at neutral loci in closely inbreeding populations.

doi:10.1093/genetics/153.3.1475

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Effect of selection against deleterious mutations on the decline in heterozygosity at neutral loci in closely inbreeding populations.

Genetics - 1 Nov 1999

Wang J, Hill W G

Abstract excerpt

Transition matrices for selfing and full-sib mating were derived to investigate the effect of selection against deleterious mutations on the process of inbreeding at a linked neutral locus. Selection was allowed to act within lines only (selection type I) or equally within and between lines (type II). For selfing lines under selection type I, inbreeding is always retarded, the retardation being determined by the...

Topics

Animals
Crosses, Genetic
Female
Genetic Linkage
Genotype
Hybrid Vigor
Inbreeding
Male
Models, Genetic
Models, Statistical
Mutation
Recombination, Genetic
Selection, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 10545475
DOI: 10.1093/genetics/153.3.1475
PMCID: PMC1460809

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics