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Article

Decline in heterozygosity under full-sib and double first-cousin inbreeding in Drosophila melanogaster.

Genetics - 1 Mar 1994

Rumball W, Franklin I R, Frankham R, Sheldon B L

Abstract excerpt

The effects of inbreeding on heterozygosities and reproductive fitness were determined by carrying out full-sib and double first-cousin inbreeding in Drosophila melanogaster populations for up to 18 generations. Parents were scored each generation for five or six polymorphic enzyme loci, and progeny numbers per pair were recorded. Inbreeding depression, in the form of significant reductions in progeny numbers and...

Topics

Alleles
Animals
Drosophila melanogaster
Female
Genes, Insect
Genes, Lethal
Genotype
Heterozygote
Homozygote
Inbreeding
Male
Polymorphism, Genetic

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Identifiers

PMID: 8005413
DOI: 10.1093/genetics/136.3.1039
PMCID: PMC1205861

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8005413-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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