Article
The change in quantitative genetic variation with inbreeding.
Evolution; international journal of organic evolution - 1 Dec 2006
Van Buskirk Josh, Willi Yvonne
Abstract excerpt
Inbreeding is known to reduce heterozygosity of neutral genetic markers, but its impact on quantitative genetic variation is debated. Theory predicts a linear decline in additive genetic variance (V(A)) with increasing inbreeding coefficient (F) when loci underlying the trait act additively, but a nonlinear hump-shaped relationship when dominance and epistasis are important. Predictions for heritability (h2) are...
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