Article
Association between keratin and vimentin expression, malignant phenotype, and survival in postmenopausal breast cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 1999
Thomas P A, Kirschmann D A, Cerhan J R, Folberg R, Seftor E A, Sellers T A, Hendrix M J
Abstract excerpt
Pathology observational reports and experimental data suggest that keratin and vimentin intermediate filament (IF) coexpression in breast cancer confers a more aggressive "interconverted" phenotype, expressing both epithelial and mesenchymal markers. In this study, we extended previous observations by measuring the expression of keratin and vimentin, in relation to other selected biomarkers of disease...
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