Article
Moesin expression is associated with the estrogen receptor-negative breast cancer phenotype.
Surgery - 1 Aug 1998
Carmeci C, Thompson D A, Kuang W W, Lightdale N, Furthmayr H, Weigel R J
Abstract excerpt
BACKGROUND: Estrogen receptor (ER)-positive breast carcinomas possess a less aggressive phenotype than ER-negative breast carcinomas. We hypothesize that a set of genes exists that is expressed only in ER-negative breast carcinomas, which account for the more malignant phenotypic characteristics...
Topics
- Blotting, Northern
- Blotting, Western
- Breast Neoplasms
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Microfilament Proteins
- Phenotype
- Proteins
- RNA, Messenger
- Receptors, Estrogen
- Tumor Cells, Cultured