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Article

Nitric oxide-induced damage to mtDNA and its subsequent repair.

Nucleic acids research - 15 Nov 1999

Grishko V I, Druzhyna N, LeDoux S P, Wilson G L

Abstract excerpt

Mutations in mitochondrial DNA (mtDNA) have recently been associated with a variety of human diseases. One potential DNA-damaging agent to which cells are continually exposed that could be responsible for some of these mutations is nitric oxide (NO). To date, little information has been forthcoming concerning the damage caused by this gas to mtDNA. Therefore, this study was designed to investigate damage to mtDNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10536162
DOI: 10.1093/nar/27.22.4510
PMCID: PMC148736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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