Article
Functional correlates of alpha(2A)-adrenoceptor gene polymorphism in the HANE study.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Nov 1999
Michel M C, Plogmann C, Philipp T, Brodde O E
Abstract excerpt
BACKGROUND: The aim of this study was to test an association between alleles of the alpha(2A)-adrenoceptor gene with hereditary hypertension and with alterations of lipid and carbohydrate metabolism. METHODS: Genomic DNA was isolated from 147 hypertensive patients and digested with DraI. Genotypes at the alpha(2A)-adrenoceptor were identified by restriction fragment length polymorphism. Genotype at each locus was...
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