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Article

Epithelial cell proliferation and gene mutation in the mucosa of gallbladder with pancreaticobiliary malunion and cancer.

Journal of hepato-biliary-pancreatic surgery - 1 Jan 1999

Obara T, Tanno S, Fujii T, Izawa T, Mizukami Y, Yanagawa N, Ura H, Kohgo Y

Abstract excerpt

The significant association between pancreaticobiliary malunion (PBM), especially undilated-type PBM, and a high risk of gallbladder cancer is known. Reflux and stasis of pancreatic juice induce various epithelial changes in the gallbladder. Recently, epithelial hyperplasia of the gallbladder was shown to be significantly and frequently associated with undilated-type PBM, and it is suggested that the majority of...

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Source

Identifiers

PMID: 10526057
DOI: 10.1007/s005340050112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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