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Article

Radiation-associated and 'spontaneous' human thyroid carcinomas show a different pattern of ras oncogene mutation.

Oncogene - 1 Mar 1991

Wright P A, Williams E D, Lemoine N R, Wynford-Thomas D

Abstract excerpt

Activated ras oncogenes in experimentally induced rodent tumours have been demonstrated to show specific patterns of oncogene activation which depend on the inducing agent, with H-ras activation in nitrosomethylurea (NMU) induced tumours, and K-ras activation in tumours induced by ionising radiation. We report a study of 12 radiation-associated human thyroid tumours, using polymerase chain reaction (PCR)...

Topics

Adenocarcinoma
Adolescent
Adult
Alleles
Carcinoma
Carcinoma, Papillary
Child
Female
Genes, ras
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Neoplasms, Radiation-Induced

Nucleic Acid Hybridization

Polymerase Chain Reaction

Thyroid Neoplasms

Source

Identifiers

PMID: 2011403

Genes

NMU

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2011403-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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