Article
Spontaneous elastic tissue lesions in the rat abdominal aorta, a genetically determined phenotype.
Journal of vascular research - 1 Jan 2000
Jones G T, Harris E L, Jacob H J, van Rij A M
Abstract excerpt
In this study, phenotypic expression of spontaneous elastic laminae defects within the rat abdominal aorta was examined. Lesions in Brown Norway (BN) rats were compared with those of New Zealand genetically hypertensive (GH) rats. BN and GH rats were cross-bred to determine the phenotypic expression of these lesions in successive F(1) and F(2) generations. Lesions were assessed by distribution, number and a...
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