Article
A novel WD40 protein, CHE-2, acts cell-autonomously in the formation of C. elegans sensory cilia.
Development (Cambridge, England) - 1 Nov 1999
Fujiwara M, Ishihara T, Katsura I
Abstract excerpt
To elucidate the mechanism of sensory cilium formation, we analyzed mutants in the Caenorhabditis elegans che-2 gene. These mutants have extremely short cilia with an abnormal posterior projection, and show defects in behaviors that are mediated by ciliated sensory neurons. The che-2 gene encodes a new member of the WD40 protein family, suggesting that it acts in protein-protein interaction. Analysis of mutation...
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