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Article

Human DNA repair disorders in dermatology: A historical perspective, current concepts and new insight.

Journal of dermatological science - 1 Feb 2016

Moriwaki Shinichi

Abstract excerpt

Products of DNA damage, such as cyclobutane pyrimidine dimers (CPDs) and pyrimidine (6-4) pyrimidone photoproducts (6-4 PPs), are continually formed in genomes after exposure to UV radiation. When these DNA damages remain unrepaired in essential DNA sites for prolonged periods, DNA replication and transcription are hampered or mutation is induced, which may cause cell death, cellular senescence, and...

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Identifiers

PMID: 26493104
DOI: 10.1016/j.jdermsci.2015.09.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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