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Article

Molecular and immunophenotypical characterization of a feline immunodeficiency virus (FIV)-associated lymphoma: a direct role for FIV in B-lymphocyte transformation?

Journal of virology - 1 Jan 1998

Beatty J A, Callanan J J, Terry A, Jarrett O, Neil J C

Abstract excerpt

We describe the histopathological, immunohistochemical, and molecular characterization of a lymphoma arising in a 7-year-old cat following experimental infection with feline immunodeficiency virus (FIV). The tumor was high grade and of B-cell lineage. The transformed cell had an immature phenotype (CD79a+, CD79b-, CD21-, immunoglobulin heavy and light chain negative), confirmed by antigen receptor gene analysis,...

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Identifiers

PMID: 9420284
DOI: 10.1128/JVI.72.1.767-771.1998
PMCID: PMC109433

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