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Cloning and Characterization of the Antiviral Activity of Feline Tetherin/BST-2

29 Mar 2011

Abstract excerpt

Human Tetherin/BST-2 has recently been identified as a cellular antiviral factor that blocks the release of various enveloped viruses. In this study, we cloned a cDNA fragment encoding a feline homolog of Tetherin/BST-2 and characterized the protein product. The degree of amino acid sequence identity between human Tetherin/BST-2 and the feline homolog was 44.4%. Similar to human Tetherin/BST-2, the expression of...

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PMID: 21479233
DOI: 10.1371/journal.pone.0018247

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