Article
Evolution of feline leukemia virus variant genomes with insertions, deletions, and defective envelope genes in infected cats with tumors.
Journal of virology - 1 Apr 1994
Rohn J L, Linenberger M L, Hoover E A, Overbaugh J
Abstract excerpt
In order to study retroviral variation, selection, and viral correlates of in vivo pathogenicity, we documented the evolution of feline leukemia virus (FeLV) variants in cats that died with thymic lymphoma after infection with molecularly cloned subgroup A FeLV. Using genomic DNA from cat necrops...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cats
- Cloning, Molecular
- Genes, env
- Genetic Variation
- Genome, Viral
- Leukemia Virus, Feline
- Lymphoma
- Molecular Sequence Data
- Mutagenesis
- Proviruses
- Retroviridae Infections
- Sequence Analysis, DNA
- Sequence Deletion
- Sequence Homology, Amino Acid
- Thymus Neoplasms