Article
1166 A/C polymorphism of the angiotensin II type 1 receptor gene and the response to short-term infusion of angiotensin II.
Circulation - 28 Sept 1999
Hilgers K F, Langenfeld M R, Schlaich M, Veelken R, Schmieder R E
Abstract excerpt
BACKGROUND: Previous studies reported an association of the 1166 A/C polymorphism of the angiotensin II (Ang II) type 1 receptor gene with high blood pressure and cardiovascular disease. We tested the hypothesis that this polymorphism affects the blood-pressure, renal hemodynamic, and aldosterone response to infused Ang II. METHODS AND RESULTS: Young, male, white volunteers (n = 116) with normal (n = 65) or...
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