Article
Starvation induces vacuolar targeting and degradation of the tryptophan permease in yeast.
The Journal of cell biology - 20 Sept 1999
Beck T, Schmidt A, Hall M N
Abstract excerpt
In Saccharomyces cerevisiae, amino acid permeases are divided into two classes. One class, represented by the general amino acid permease GAP1, contains permeases regulated in response to the nitrogen source. The other class, including the high affinity tryptophan permease, TAT2, consists of the so-called constitutive permeases. We show that TAT2 is regulated at the level of protein stability. In exponentially...
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