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Article

Development of phenotypic HIV-1 drug resistance after exposure to single-dose nevirapine.

Journal of acquired immune deficiency syndromes (1999) - 15 Dec 2008

Basson Adriaan E, Ntsala Matshediso, Martinson Neil, Tlale Emily, Corrigan Gary E, Shao Xingwu, Gray Glenda, McIntyre James, Puren Adrian, Morris Lynn

Abstract excerpt

OBJECTIVES: Single-dose nevirapine (sdNVP) used to prevent mother-to-child transmission of HIV-1 results in the selection of genotypic drug resistance mutations. To assess the levels of phenotypic resistance conferred by these mutations, we examined the ability of sample-derived HIV-1 reverse transcriptase to function in the presence of nevirapine (NVP). METHODS: Plasma samples from HIV-1 pregnant women before...

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Source

Identifiers

PMID: 18989222
DOI: 10.1097/QAI.0b013e31818d5dcf

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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