Article
A rapid non-culture-based assay for clinical monitoring of phenotypic resistance of human immunodeficiency virus type 1 to lamivudine (3TC).
Antimicrobial agents and chemotherapy - 1 Feb 1999
García Lerma J, Schinazi R F, Juodawlkis A S, Soriano V, Lin Y, Tatti K, Rimland D, Folks T M, Heneine W
Abstract excerpt
Monitoring for lamivudine (3TC) resistance is important both for the clinical management of human immunodeficiency virus type 1 (HIV-1)-infected patients treated with 3TC and for surveillance of transmission of 3TC-resistant HIV-1. We developed a novel non-culture-based assay for the rapid analysis of phenotypic resistance to 3TC of HIV-1 in plasma. The assay measures the susceptibility of HIV-1 reverse...
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