Article
A rapid non-culture-based assay for clinical monitoring of phenotypic resistance of human immunodeficiency virus type 1 to lamivudine (3TC).
Antimicrobial agents and chemotherapy - 1 Feb 1999
García Lerma J, Schinazi R F, Juodawlkis A S, Soriano V, Lin Y, Tatti K, Rimland D, Folks T M, Heneine W
Abstract excerpt
Monitoring for lamivudine (3TC) resistance is important both for the clinical management of human immunodeficiency virus type 1 (HIV-1)-infected patients treated with 3TC and for surveillance of transmission of 3TC-resistant HIV-1. We developed a novel non-culture-based assay for the rapid analys...
Topics
- Anti-HIV Agents
- Drug Resistance, Microbial
- Drug Resistance, Multiple
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Lamivudine
- Microbial Sensitivity Tests
- Phenotype
- Reverse Transcriptase Inhibitors