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Article

Natural and iatrogenic variation in hepatitis B virus.

Reviews in medical virology - 1 Jul 1999

Ngui S L, Hallet R, Teo C G

Abstract excerpt

The existence of HBV as quasispecies is thought to be favoured by the infidelity of HBV RT, which would account for the emergence of the many natural mutants with point substitutions. RT infidelity may also underlie the hypermutation phenomenon. Indeed, the oft-reported point mutation in the preC gene that leads to failure of HBeAg synthesis may be driven by a hypermutation-related mechanism. The presence of...

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Identifiers

PMID: 10479779
DOI: 10.1002/(sici)1099-1654(199907/09)9:3<183::aid-rmv248>3.0.co;2-p

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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