Article
Dlx-5 in limb initiation in the chick embryo.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Sept 1999
Ferrari D, Harrington A, Dealy C N, Kosher R A
Abstract excerpt
Dlx-5 is a vertebrate homolog of the Drosophila Distal-less gene, one of the first genetic signals for limb formation in the fly. In the present study we have explored the possible role of Dlx-5 in limb initiation in the chick embryo. At stage 14 which is well before the initial formation of limb buds Dlx-5 is highly and specifically expressed in the ectoderm of the presumptive wing and leg forming regions of the...
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