Article
Characterization of fmtA, a gene that modulates the expression of methicillin resistance in Staphylococcus aureus.
Antimicrobial agents and chemotherapy - 1 Sept 1999
Komatsuzawa H, Ohta K, Labischinski H, Sugai M, Suginaka H
Abstract excerpt
FmtA is a factor which affects the methicillin resistance level in methicillin-resistant Staphylococcus aureus. Since FmtA has two of three conserved motifs which are typically found in penicillin-binding proteins (PBPs) and beta-lactamases, we investigated the penicillin-binding activity of recombinant FmtA and found no such activity. Immunoblotting analysis revealed that FmtA localizes in the membrane fraction....
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