Article
Normally functioning murF is essential for the optimal expression of methicillin resistance in Staphylococcus aureus.
Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 2003
Sobral R G, Ludovice A M, Gardete S, Tabei K, De Lencastre H, Tomasz A
Abstract excerpt
A carboxy-terminal fragment of murF was used to construct and insert a suicide plasmid into the chromosomal copy of the gene in the highly and homogeneously methicillin-resistant Staphylococcus aureus (MRSA) strain COL by Campbell type integration. The plasmid insertion generated a mutant in whic...
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