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Article

Haemophilia B carrier detection by factor IX:C analysis; no impact of the type of mutation or severity of disorder.

Haemophilia : the official journal of the World Federation of Hemophilia - 1 Jul 1999

Knobe K E, Ljung R C

Abstract excerpt

Haemophilia B, an X-linked recessive bleeding disorder characterized by lack or deficiency of factor IX, has been shown to be caused by any of a variety of DNA abnormalities (partial or total deletions, nonsense or missense mutations). Since in most countries carrier detection is based on factor IX coagulant activity (FIX:C) assay, this study was designed to determine whether carriers' FIX:C values are dependent...

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Source

Identifiers

PMID: 10469176
DOI: 10.1046/j.1365-2516.1999.00331.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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