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Article

Molecular defects in haemophilia B: detection by direct restriction enzyme analysis.

British journal of haematology - 1 Sept 1991

Chan V V, Yip B, Tong T M, Chan T P, Lau K, Yam I, Chan T K

Abstract excerpt

The common restriction fragment length polymorphisms (RFLPs) associated with the FIX gene: 5' BamH I, Dde I, BamH I (2), Taq I and 3' Hha I were absent or of low incidence in Southern Chinese and are therefore not useful for linkage analysis. No deletion was detected amongst seven consecutive unrelated haemophilia B patients, but one had an insertion of a 15 kb Pvu II fragment containing exon d. Using an...

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Identifiers

PMID: 1680373
DOI: 10.1111/j.1365-2141.1991.tb08008.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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