Article
No genetic association between polymorphisms in the Tau gene and Alzheimer's disease in clinic or population based samples.
Neuroscience letters - 14 May 1999
Crawford F, Freeman M, Town T, Fallin D, Gold M, Duara R, Mullan M
Abstract excerpt
Mutations in the tau protein gene have recently been found to cause familial fronto-temporal dementia in a number of kindreds demonstrating linkage to chromosome 17. Given that tau pathology is a hallmark of Alzheimer's disease (AD), this raises the possibility that mutations in tau may also be associated with AD. We have investigated the allelic frequencies of polymorphisms in the Tau gene for a possible allelic...
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