Article
Pathogenesis of chronic hepatitis C: immunological features of hepatic injury and viral persistence.
Hepatology (Baltimore, Md.) - 1 Sept 1999
Cerny A, Chisari F V
Abstract excerpt
The immune response to viral antigens is thought to be responsible for viral clearance and disease pathogenesis during hepatitis C virus (HCV) infection. In chronically infected patients, the T-cell response to the HCV is polyclonal and multispecific, although it is not as strong as the response in acutely infected patients who display a more vigorous T-cell response. Importantly, viral clearance in acutely...
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