Article
[Immunopathogenesis of viral hepatitis].
Praxis - 4 Apr 2007
Neumann-Haefelin C, Thimme R
Abstract excerpt
The different components of the immune system play important roles in the outcome of hepatitis B and C. In > 90% of HBV-infected individuals, these immune responses successfully clear the virus, while 50-80% of chronically HCV-infected individuals experience viral persistence. During the last years, the mechanisms of viral persistence, e.g. viral escape mutations and T cell dysfunction, have been characterised in...
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