Article
Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems.
Proceedings of the National Academy of Sciences of the United States of America - 17 Aug 1999
Akamatsu W, Okano H J, Osumi N, Inoue T, Nakamura S, Sakakibara S, Miura M, Matsuo N, Darnell R B, Okano H
Abstract excerpt
Hu proteins are mammalian embryonic lethal abnormal visual system (ELAV)-like neuronal RNA-binding proteins that contain three RNA recognition motifs. Although Drosophila ELAV is required for the correct differentiation and survival of neurons, the roles played by the Hu genes in the mammalian nervous system remain largely unknown. To explore the in vivo functions of mouse Hu proteins, we overexpressed them in...
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