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Article

No support for HLA-DQ encoded susceptibility in rheumatoid arthritis.

Arthritis and rheumatism - 1 Aug 1999

de Vries N, van Elderen C, Tijssen H, van Riel P L, van de Putte L B

Abstract excerpt

OBJECTIVE: To test predictions based on data from immunogenetic and peptide-binding studies of collagen-induced arthritis in mice, in which it has been suggested that susceptibility to rheumatoid arthritis (RA) might be determined by the interaction between susceptibility alleles at the HLA-DQ locus and protective alleles at the HLA-DRB1 locus (including susceptibility effects for HLA-DQ7 and DQ8). METHODS:...

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Source

Identifiers

PMID: 10446860
DOI: 10.1002/1529-0131(199908)42:8<1621::AID-ANR9>3.0.CO;2-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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No support for HLA-DQ encoded susceptibility in rheumatoid arthritis.PMID 10446860Read ↗

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Investigating the HLA component in rheumatoid arthritis: an additive (dominant) mode of inheritance is rejected, a recessive mode is preferred.Semantic proximity Read ↗

Lack of influence of non-inherited maternal HLA-DR alleles on susceptibility to rheumatoid arthritis.Semantic proximity Read ↗

Naturally processed peptides from HLA-DQ7 (alpha1*0501-beta1*0301): influence of both alpha and beta chain polymorphism in the HLA-DQ peptide binding specificity.Semantic proximity Read ↗

Genetics of rheumatoid arthritis.Semantic proximity Read ↗

The HLA-DQ7 and -DQ8 associations in DR4-positive rheumatoid arthritis patients. A combined analysis of data available in the literature.Semantic proximity Read ↗

A spectrum of susceptibility to rheumatoid arthritis within HLA-DRB1: stratification by autoantibody status in a large UK population.Semantic proximity Read ↗

Reshaping the shared epitope hypothesis: HLA-associated risk for rheumatoid arthritis is encoded by amino acid substitutions at positions 67-74 of the HLA-DRB1 molecule.Semantic proximity Read ↗

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