Article
The humoral immune response against an HLA class I allodeterminant correlates with the HLA-DR phenotype of the responder.
Transplantation - 27 Jul 1999
Fuller T C, Fuller A
Abstract excerpt
BACKGROUND: The genetic basis for control of alloantibody responses against foreign HLA histocompatibility antigens has never been delineated. The most likely postulate would be that HLA class II alloantigens of the host regulate the response through their ability to present processed HLA allopeptide fragments for the cognate interaction between CD4+ T lymphocytes and B lymphocytes that leads to IgG antibody...
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