Deleterious impact of HLA-DRB1 allele mismatch in sensitized recipients of kidney retransplants.

doi:10.1097/TP.0b013e318277e277

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Article

Deleterious impact of HLA-DRB1 allele mismatch in sensitized recipients of kidney retransplants.

Transplantation - 15 Jan 2013

Heinold Andreas, Opelz Gerhard, Döhler Bernd, Unterrainer Christian, Scherer Sabine, Ruhenstroth Andrea, Hien Tran Thuong

Abstract excerpt

BACKGROUND: Whether mismatches between donor and recipient of a kidney transplant at the HLA allele level can elicit an immune response strong enough to impact graft survival is not known. METHODS: We examined the influence of HLA-DRB1 allele level mismatch on graft survival based on high-resolution typing, utilizing blood samples and clinical data provided by the Collaborative Transplant Study. HLA-DRB1*04 was...

Topics

Adolescent
Adult
Aged
Alleles
Female
Graft Survival
HLA-DRB1 Chains
Histocompatibility Testing
Humans
Kidney Transplantation
Male
Middle Aged
Proportional Hazards Models

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Open in PubMed

Identifiers

PMID: 23183775
DOI: 10.1097/TP.0b013e318277e277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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