Article
Differences in immunogenicity of HLA antigens and the impact of cross-reactivity on the humoral response.
Transplantation - 1 Jan 2015
Lucas Donna P, Leffell Mary S, Zachary Andrea A
Abstract excerpt
BACKGROUND: Information about differences in immunogenicity of various HLA antigens may help guide donor selection and identify mismatches to avoid for patients likely to need retransplantation. To date, antibody responses to a wide array of individual mismatched antigens have not been evaluated. METHODS: Frequencies of antibodies to mismatched HLA-A, HLA-B, HLA-DR, and HLA-DQ antigens were determined for 703...
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