Article
Is there MHC Class II restriction of the response to MHC Class I in transplant patients?
Transplantation - 27 Feb 2002
Papassavas Andreas C, Barnardo Martin C N M, Bunce Mike, Welsh Kenneth I
Abstract excerpt
BACKGROUND: In this study, we evaluated distinct HLA-DRB1 alleles to determine class II restriction of the production of HLA-A2-specific antibodies in renal transplant patients. METHODS: Data from 217 renal transplant patients who received an HLA-A2-mismatched renal graft were analyzed with regard to HLA-A2 humoral responsiveness. High-resolution DNA typing of class II HLA-DR alleles was performed by polymerase...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.