Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recycling of a single human blastomere fixed on a microscopic slide for sexing and diagnosis of specific mutations by various types of polymerase chain reaction.

Fertility and sterility - 1 Aug 1999

He Z Y, Liu H C, Mele C A, Veeck L L, Davis O, Rosenwaks Z

Abstract excerpt

OBJECTIVE: To investigate the suitability of recycling single blastomeres to assess multiple genetic variables for preimplantation genetic diagnosis. DESIGN: Prospective randomized study. SETTING: An academic medical center. PATIENT(S): Patients undergoing IVF-ET. INTERVENTION(S): Blastomeres were disaggregated from donated embryos obtained from patients. MAIN OUTCOME MEASURE(S): Polymerase chain reaction (PCR)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blastomeres
Share to DNA, Satellite

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Embryo Transfer

Share to Fertilization in Vitro

Share to In Vitro Techniques

Share to Sex Determination Analysis

Share to X Chromosome

Share to Y Chromosome

Source

Identifiers

PMID: 10439008
DOI: 10.1016/s0015-0282(99)00241-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recycling of a single human blastomere fixed on a microscopic slide for sexing and diagnosis of specific mutations by various types of polymerase chain reaction.PMID 10439008Read ↗

Allele dropout in sequential PCR and FISH analysis of single cells (cell recycling).Semantic proximity Read ↗

Single cell polymerase chain reaction for preimplantation genetic diagnosis: methods, strategies, and limitations.Semantic proximity Read ↗

Preimplantation genetic diagnosis for chromosome rearrangements – one blastomere biopsy versus two blastomere biopsySemantic proximity Read ↗

Reliable gender screening for human preimplantation embryos, using multiple DNA target-sequencesSemantic proximity Read ↗

[Sex determination of human preimplantation embryo using nested polymerase chain reaction].Semantic proximity Read ↗

Preclinical models for human pre-embryo biopsy and genetic diagnosis. II. Polymerase chain reaction amplification of deoxyribonucleic acid from single lymphoblasts and blastomeres with mutation detection.Semantic proximity Read ↗

Detailed investigation of factors influencing amplification efficiency and allele drop-out in single cell PCR: implications for preimplantation genetic diagnosis.Semantic proximity Read ↗

Fluorescent PCR: a new technique for PGD of sex and single-gene defects.Semantic proximity Read ↗

Modification of the triplet repeat primed polymerase chain reaction method for detection of the CTG repeat expansion in myotonic dystrophy type 1: application in preimplantation genetic diagnosis.Semantic proximity Read ↗

Allelic drop-out and preferential amplification in single cells and human blastomeres: implications for preimplantation diagnosis of sex and cystic fibrosis.Semantic proximity Read ↗

Adaptation of the primer extension preamplification (PEP) reaction for preimplantation diagnosis: single blastomere analysis using short PEP protocolsSemantic proximity Read ↗

Hematoxylin and Eosin Staining Helps Reduce Maternal Contamination in Short Tandem Repeat Genotyping for Hydatidiform Mole Diagnosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.