Article
A null mutation in the inflammation-associated S100 protein S100A8 causes early resorption of the mouse embryo.
Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 1999
Passey R J, Williams E, Lichanska A M, Wells C, Hu S, Geczy C L, Little M H, Hume D A
Abstract excerpt
S100A8 (also known as CP10 or MRP8) was the first member of the S100 family of calcium-binding proteins shown to be chemotactic for myeloid cells. The gene is expressed together with its dimerization partner S100A9 during myelopoiesis in the fetal liver and in adult bone marrow as well as in mature granulocytes. In this paper we show that S100A8 mRNA is expressed without S100A9 mRNA between 6.5 and 8. 5 days...
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