Article
Antagonistic substrate binding by a group II intron ribozyme.
Journal of molecular biology - 6 Aug 1999
Qin P Z, Pyle A M
Abstract excerpt
In this study, the thermodynamic properties of substrate-ribozyme recognition were explored using a system derived from group II intron ai5gamma. Substrate recognition by group II intron ribozymes is of interest because any nucleic ac?id sequence can be targeted, the recognition sequence can be quite long (>/=13 bp), and reaction can proceed with a very high degree of sequence specificity. Group II introns target...
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