Article
Rifins: a second family of clonally variant proteins expressed on the surface of red cells infected with Plasmodium falciparum.
Proceedings of the National Academy of Sciences of the United States of America - 3 Aug 1999
Kyes S A, Rowe J A, Kriek N, Newbold C I
Abstract excerpt
Many pathogens evade the host immune response or adapt to their environment by expressing surface proteins that undergo rapid switching. In the case of Plasmodium falciparum, products of a multigene family known as var are expressed on the surface of infected red cells, where they undergo clonal antigenic variation and contribute to malaria pathogenesis by mediating adhesion to a variety of host endothelial...
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