Article
Evidence for a dynamic role for proline376 in the purine-cytosine permease of Saccharomyces cerevisiae.
European journal of biochemistry - 1 Jul 1999
Ferreira T, Napias C, Chevallier J, Brèthes D
Abstract excerpt
The purine-cytosine permease (PCP), a carrier located in the plasma membrane of Saccharomyces cerevisiae, mediates the active transport of purine (adenine, guanine and hypoxanthine) and cytosine into the cell. Previous studies [Ferreira, T, Brèthes, D., Pinson, B., Napias, C. & Chevallier, J. et al. (1997) J. Biol. Chem. 272, 9697-9702] suggest that the hydrophilic segment 371-377 (-I-A-N-N-I-P-N-) of the...
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