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Article

Replacement of Lys by Glu in a transmembrane segment strongly impairs the function of the uracil permease from Saccharomyces cerevisiae.

The Biochemical journal - 15 Jun 1995

Urban-Grimal D, Pinson B, Chevallier J, Haguenauer-Tsapis R

Abstract excerpt

The co-transport of uracil and protons through the plasma membrane of the yeast Saccharomyces cerevisiae is mediated by a specific permease encoded by the FUR4 gene. The uracil permease is a multi-spanning membrane protein that follows the secretory pathway to the plasma membrane. Recent experimental data led to the proposal of a two-dimensional model of its topology. A spontaneous mutant corresponding to the...

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Identifiers

PMID: 8948441
DOI: 10.1042/bj3080847
PMCID: PMC1136801

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Replacement of Lys by Glu in a transmembrane segment strongly impairs the function of the uracil permease from Saccharomyces cerevisiae.PMID 8948441Read ↗

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The study of methionine uptake in Saccharomyces cerevisiae reveals a new family of amino acid permeases.Semantic proximity Read ↗

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