Article
Epidemiology of the genetic elements responsible for acquired glycopeptide resistance in enterococci.
Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 2001
Woodford N
Abstract excerpt
Five genotypes of acquired glycopeptide resistance have been documented in enterococci, with vanA and vanB being the most globally widespread and prevalent. Resistance results from the production of peptidoglycan precursors with reduced binding affinity for glycopeptides and is encoded by complex clusters of van genes. The prototype VanA element is Tn1546, a 10.8-kb transposon that carries the vanRSHAXYZ genes....
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