Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Selection of phenotypically distinct NK1.1+ T cells upon antigen expression in the thymus or in the liver.

European journal of immunology - 1 Jul 1999

Legendre V, Boyer C, Guerder S, Arnold B, Hämmerling G, Schmitt-Verhulst A M

Abstract excerpt

Unlike the main TCR alphabeta T cell lineage in which deletion occurs at the CD4+ CD8+ double-positive (DP) stage upon TCR engagement by antigen in the thymus, some T cells appear to require such engagement for their selection, either in the thymus or extrathymically. We used a transgenic TCR (tgTCR) model which, as we previously showed, led to selection upon expression of the corresponding antigen H-2Kb (Kb) in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Ly
Share to CD8 Antigens
Share to H-2 Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyaluronan Receptors

Share to Lectins, C-Type

Share to Mice, Inbred CBA

Share to Receptors, Antigen, T-Cell, alpha-beta

Share to Receptors, Interleukin-2

Source

Identifiers

PMID: 10427996
DOI: 10.1002/(SICI)1521-4141(199907)29:07<2330::AID-IMMU2330>3.0.CO;2-G

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Selection of phenotypically distinct NK1.1+ T cells upon antigen expression in the thymus or in the liver.PMID 10427996Read ↗

Intensive generation of NK1.1- extrathymic T cells in the liver by injection of bone marrow cells isolated from mice with a mutation of polymorphic major histocompatibility complex antigens.Semantic proximity Read ↗

Stringent V beta requirement for the development of NK1.1+ T cell receptor-alpha/beta+ cells in mouse liver.Semantic proximity Read ↗

MicroRNA-181a/b-1 Is Not Required for Innate γδ NKT Effector Cell Development.Semantic proximity Read ↗

A subset of CD4+ thymocytes selected by MHC class I molecules.Semantic proximity Read ↗

Positive selecting cell type determines the phenotype of MHC class Ib-restricted CD8+ T cells.Semantic proximity Read ↗

Origin of regulatory T cells with known specificity for antigen.Semantic proximity Read ↗

Phenotypic changes accompanying positive selection of CD4+CD8+ thymocytes.Semantic proximity Read ↗

The fas antigen is involved in thymic T-cell development as a costimulatory molecule, but not in the deletion of neglected thymocytes.Semantic proximity Read ↗

Repertoire development and ligand specificity of murine TCR gamma delta cells.Semantic proximity Read ↗

Decreased expression of the interleukin 2 receptor on CD8 recipient lymphocytes in intestinal grafts rendered tolerant by liver transplantation in rats.Semantic proximity Read ↗

T cells with dual antigen specificity in T cell receptor transgenic mice rejecting allografts.Semantic proximity Read ↗

Discrimination between thymic epithelial cells and peripheral antigen-presenting cells in the induction of immature T cell differentiation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.