Article
Production and characterisation of deletion mutants of ovine growth hormone.
Journal of molecular endocrinology - 1 Aug 1999
Sami A J, Wallis O C, Wallis M
Abstract excerpt
A number of analogues of ovine growth hormone (GH), in which regions of the hormone had been deleted, were produced by site-directed mutagenesis, and characterised by radioimmunoassays and radioreceptor assays. These analogues were based on a previously described variant (oGH1) in which an 8-residue extension replaces the N-terminal alanine of pituitary-derived ovine GH. Three analogues with deletions near the...
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