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Article

A method for determining transmembrane helix association and orientation in detergent micelles using small angle x-ray scattering.

Biophysical journal - 1 Aug 1999

Bu Z, Engelman D M

Abstract excerpt

Solution small angle x-ray scattering can be used to study the association of transmembrane proteins solubilized in detergent micelles. We have used the alpha-helical transmembrane domain of the human erythrocyte glycophorin A (GpA) fused to the carboxyl terminus of monomeric staphylococcal nuclease (SN/GpA) as a model system for study. By matching the average electron density of the detergent micelles to that of...

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Identifiers

PMID: 10423450
DOI: 10.1016/S0006-3495(99)76956-0
PMCID: PMC1300396

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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