Article
Influence of hydrophobic matching on association of model transmembrane fragments containing a minimised glycophorin A dimerisation motif.
FEBS letters - 14 Mar 2005
Orzáez Mar, Lukovic Dunja, Abad Concepción, Pérez-Payá Enrique, Mingarro Ismael
Abstract excerpt
The principles that govern the folding and packing of membrane proteins are still not completely understood. In the present work, we have revisited the glycophorin A (GpA) dimerisation motif that mediates transmembrane (TM) helix association, one of the best-suited models of membrane protein oligomerisation. By using artificial polyleucine TM segments we have demonstrated in this study that a pattern of only five...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
