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Article

Are salivary glands cell lines in culture a good model for purinergic receptors in salivary glands?

Archives of oral biology - 1 May 1999

Carmel Z, Amsallem H, Métioui M, Dehaye J P, Moran A

Abstract excerpt

A major obstacle in studying the physiological and biochemical processes of salivary secretion is the lack of a good ductal cell line model. HSY, an immortalised cell line originating from human parotid gland intercalated ducts, provides a possible model for purinergic mechanisms in ductal cells. Unlike the biphasic dose response to ATP of isolated submandibular ductal cells, the rise in [Ca2+]i in HSY cells...

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PMID: 10414859
DOI: 10.1016/s0003-9969(99)90024-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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