Is Repair of DNA Strand Break Damage from Ionizing Radiation Second-Order Rather Than First-Order? A Simpler Explanation of Apparently Multiexponential Repair

Abstract excerpt

The purpose of this paper is to suggest the hypothesis that repair of radiation damage might be largely a second-order process (binary), as well as or instead of first-order (monoexponential). Second-order means that the rate of repair is proportional to n(2) instead of to n, where n is the number of repairable breaks. Integrating this equation gives a linear plot of the reciprocal proportion of unrepaired...

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